ABSTRACT
Objective To detect the level of S100-β protein in the serum of patients with closed craniocerebral injury and analyze its clinical value to assess the diagnosis and prognosis of the disease.Methods The expression of quantitative analysis method to detect 31 cases of healthy control group,40 cases of patients with severe craniocerebral injury and 34 cases of craniocerebral injury patients on admission S100-β protein level by the receiver operating characteristic curve (ROC) analysis,to explore the correlation between the prognosis of GOS,closed craniocerebral injury diagnosis efficacy.Results In the control group,mild and severe closed craniocerebral injury group S100-β protein levels were 0.137 ±0.025,0.192 ± 0.038 and 0.276 ±0.097 ng/ml,respectively.Compared with the control group (F=0.126,P=0.008),light and heavy closed craniocerebral injury group (F=38.17,P=0.001) of serum S100-β protein levels were significantly increased,the difference was statistically significant (P＜0.01).There were significant differences in the level of serum S100-β light and heavy craniocerebral injury group (P＜0.05).Serum S100-βprotein differential control group and brain injury group AUC 0.870 (95％ CI:0.776 ～ 0.964,P＜ 0.01).S100-β protein identification in healthy control group with severe craniocerebral injury group AUC was 0.914 (95 ％ CI:0.850～0.978,P＜ 0.01).The score was negatively correlated with serum S100-β protein level and the prognosis of craniocerebral injury in GOS (r=-0.792,P＜0.01).Conclusion S100-β protein significantly increased in serum of light and heavy closed craniocerebral injury patients,and negatively correlated with the GOS score of patients,can be used for the auxiliary diagnosis and prognosis of craniocerebral injury.
ABSTRACT
<p><b>OBJECTIVE</b>To explore a treatment program for increasing therapeutic effect on rheumatoid arthritis at active stage.</p><p><b>METHODS</b>One hundred and forty-six cases were randomly divided into treatment group (n = 74) and medicine control group (n = 72). The treatment group were treated by electroacupuncture at Quchi (LI 11), Hegu (LI 4), Yanglingquan (GB 34), etc. , combined with meloxicam, sulfasalazine and MTX. The control group treated by simple the Western medicines. Their therapeutic effects were compared.</p><p><b>RESULTS</b>The effective rate was 79.73% in the treatment group and 51.39% in the control group with a significant difference between the two groups (P< 0. 05).</p><p><b>CONCLUSION</b>Electroacupuncture combined with medicine has a better therapeutic effect than the simple medicine on rheumatoid arthritis at active stage.</p>